Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands  for Positron Emission Tomography Imaging

Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging

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11C-Labeled Radiotracer for Noninvasive and Quantitative Assessment of the Thiocyanate Efflux System in the Brain

Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders - Bonifazi - 2023 - Medicinal Research Reviews - Wiley Online Library

Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

Two-improved-routes-11C-PET

Synthesis and biological evaluation of novel 18F-labeled phenylbenzofuran-2-carboxamide derivative for detection of orexin 1 receptor in the brain - ScienceDirect

Frontiers Development of a Novel Positron Emission Tomography (PET) Radiotracer Targeting Bromodomain and Extra-Terminal Domain (BET) Family Proteins

Synthesis and preclinical evaluation of [11C]MTP38 as a novel PET ligand for phosphodiesterase 7 in the brain

PDF) Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging

Beyond monoamines: I. Novel targets and radiotracers for Positron emission tomography imaging in psychiatric disorders - Lopresti - 2023 - Journal of Neurochemistry - Wiley Online Library

Synthesis of [11C]MK-1064 as a new PET radioligand for imaging of orexin-2 receptor - ScienceDirect

Kinetics time course for the association (A, C, and E) and dissociation

Full article: Synthesis and Characterization of a New Carbon-11 Labeled Positron Emission Tomography Radiotracer for Orexin 2 Receptors Neuroimaging

Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders - Bonifazi - 2023 - Medicinal Research Reviews - Wiley Online Library

Tracer evaluation strategy. Step 1 and 2: Traditionally, specific